Evaluation of the antibacterial activities of methanol stem extract of Massularia acuminata and methanol twig extract of Garcinia kola on oral Bacteria and their effect in combination

Massularia acuminata and Garcinia kola are chewing sticks widely used in Nigeria rural population for oral dental care. This research investigates the individual antibacterial effects of methanol extracts stem twigs these plants respectively combined effect both extracts, against isolates cavity. The were obtained from cavities healthy undergraduate students. bacteria Staphylococcus aureus, Klebsiella pneumonia, Streptococcus spp., Pseudomonas aeruginosa Escherichia coli. Screening each extract on standardized was done by Agar well diffusion method. On S. M. acuminate G. had minimum inhibitory concentration (MIC) 12.5mg/ml with mean zone diameter (IZD) 3mm 10mm respectively. combination plant showed MIC 25mg/ml a IZD 4mm. E. coli, 2mm gave 1mm. Both didn’t exhibit any other 3 isolates. Statistical analysis using ANOVA values significant at p<0.05 activity kola, also (p<0.05) coli but insignificant (p>0.05). study proved that can be hygiene, not